NSW Health safety notice on risk of toxicity from ‘colic preparations’ containing belladonna

There have been ongoing reports of neonates/infants in the community presenting to GPs or hospital emergency departments with suspected anticholinergic syndrome, which may occur after administration of a ‘colic preparation’ purchased online that contains belladonna. Similar cases have also been reported in other jurisdictions.

This Safety Notice is to inform NSW Health clinicians of the risk of toxicity associated with ‘colic preparations’ containing belladonna and advise that a heightened degree of suspicion for belladonna toxicity is warranted when assessing neonates/infants presenting with symptoms of anticholinergic syndrome.

Please ensure you read the full notice, including background, assessment and recommendations.